With Rasmus Hojlund still sidelined, Zirkzee will hope he has done enough to earn his place in the starting XI to lead United’s attack this weekend.
Alejandro Garnacho is another who is only recently back in Manchester, coming off the bench in the Community Shield against Manchester City and again against Fulham.
The Argentina international didn’t look quite up to speed against the Cottagers, which could see Amad Diallo keep his place in the side.
With Luke Shaw still sidelined, Diogo Dalot is expected to continue at left-back with Noussair Mazraoui enjoying a fine debut on the right.
Harry Maguire meanwhile limped off that night and while Ten Hag later explained his withdrawal was a precautionary measure, it could open up room for Matthijs de Ligt to make his full debut against Brighton.
Manchester United 4-2-3-1 lineup
Manchester United Predicted XI to face Brighton: Onana, Mazraoui, De Ligt, Martinez, Dalot, Casemiro, Mainoo, Amad, Fernandes, Rashford, Zirkzee
Date And Kick-off time: Brighton vs Man Utd kicks off at 12:30pm on Saturday 24 August
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